After a car crash sends repressed cartoonist Stu into a coma, he and the mischievous Monkeybone, his hilarious alter-ego, wake up in a wacked-out waystation for lost souls. When Monkeybone takes over Stu's body and escapes to wreak havoc on the real world, Stu has to find a way to stop him before his sister pulls the plug on reality forever!
- Year: 2001
- Country: United States of America
- Genre: Adventure, Fantasy, Animation, Comedy, Science Fiction
- Studio: 1492 Pictures, Twitching Image Studio, 20th Century Fox
- Keyword: coma, based on comic, stop motion, parallel world, organ donation, horniness agent, aftercreditsstinger, cartoonist, live action and animation, live action
- Director: Henry Selick
- Cast: Brendan Fraser, Bridget Fonda, John Turturro, Chris Kattan, Giancarlo Esposito, Rose McGowan